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Pre-implantation Genetic Diagnosis (PGD)

Diagnóstico Genético There are many genetic diseases than can be transferred from parents to children such as hemophilia, Tay-Sachs, cystic fibrosis, sickle cell anemia, and Down’s syndrome. Pre-implantation Genetic Diagnosis (PGD) is a reproductive technology that was developed to screen embryos for genetic or chromosomal disorders in order to select those that are healthy and disease-free.

 

An embryo with too many or too few chromosomes will either fail to implant in the uterus, lead to a miscarriage, or result in a chromosomal birth defect.

 

As such, this technique is suitable for couples in the following cases:

 

Patients over 30 years of age with a high risk of alterations in chromosomal numbers.

Couples with risk of transmission of any genetic disease.

Patients with a history of several failed IVF procedures.

Patients with a history of repeated miscarriage/abortion.

 

With biologists specialized in genetics and molecular biology, after our clinical geneticists study each specific case, strategies are prepared to diagnose diseases in the embryos, by studying their chromosomes or by detecting the genetic changes that cause monogenetic diseases.

 

Using micromanipulation techniques, each embryo is biopsied by extracting one or two cells. The nuclei of the samples are then analyzed by marking their chromosomes with fluorescent probes and analyzing them for various changes. In the meantime, the embryo is maintained in culture, awaiting transfer as soon as the diagnosis is known.

 

Because the gender chromosomes are identified during PGD, it is possible to select a male or female embryo for transfer to the uterus. Gender selection is prohibited by legislation in Spain except for cases of sex linked genetic diseases.

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HOSPITALES, S.L.U. ensures that all data collected through the online form will be used in the manner and with the limitations and rights provided for in Organic Law 15/1999 of December 13 on the Protection of Personal Data (LOPD). The processing and management of this data meet the provisions of Royal Decree 994/1999, of 11 June, which approves the Regulation on security measures for automated files containing personal data.

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HOSPITALES, S.L.U. ensures that all data collected through the online form will be used in the manner and with the limitations and rights provided for in Organic Law 15/1999 of December 13 on the Protection of Personal Data (LOPD). The processing and management of this data meet the provisions of Royal Decree 994/1999, of 11 June, which approves the Regulation on security measures for automated files containing personal data.